Fildena: A Pharmacological Overview

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Attribute Details
Generic Name Sildenafil
Dosage Forms 25 mg, 50 mg, 100 mg
Indication Erectile Dysfunction
Pharmacokinetics Absorbed orally, metabolized in the liver
Contraindications Nitrate therapy, severe cardiovascular disorders
Common Side Effects Headache, flushing, dyspepsia
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Pharmacokinetics

Fildena’s active ingredient, sildenafil, belongs to the phosphodiesterase type 5 inhibitor class. Its primary role is facilitating increased blood flow to the penis during sexual arousal. This aids in achieving and maintaining an erection. Absorption occurs rapidly when administered orally. Peak plasma concentrations reach approximately one hour after ingestion. However, high-fat meals can delay its absorption.

Once in the bloodstream, sildenafil is distributed extensively into tissues. It exhibits a half-life of around four hours. Liver enzymes, primarily CYP3A4, metabolize the compound. Excretion is predominantly through feces, with renal clearance playing a smaller role. This pharmacokinetic profile supports its efficacy and duration of action, which typically lasts up to four hours.

Fildena Use

Fildena, available in doses like sildenafil 100 mg, is primarily prescribed for erectile dysfunction. This condition affects many men, impacting both physical and emotional health. Fildena enhances erectile function, fostering confidence and improving quality of life.

Patients should adhere to prescribed doses and guidelines. It’s recommended to take Fildena about one hour before anticipated sexual activity. However, it can be taken anywhere from 30 minutes to four hours in advance. Effectiveness depends on individual response and concurrent factors like food intake.

Fildena Contraindications

Fildena, including dosages such as sildenafil 50 mg, is contraindicated in patients using nitrates. This combination can lead to severe hypotension. Those with cardiovascular diseases should also exercise caution. Physicians assess risk factors, considering overall health status before prescribing.

Severe liver impairment and end-stage renal disease pose additional contraindications. Such conditions can alter Fildena’s metabolism and excretion. Patients with hypersensitivity to sildenafil or any tablet constituents must avoid use.

Fildena Interactions

Numerous medications can interact with Fildena, affecting its efficacy and safety. CYP3A4 inhibitors, like ketoconazole, may increase sildenafil levels. This can amplify side effects. Conversely, CYP3A4 inducers can reduce its effectiveness.

Co-administration with alpha-blockers requires caution. This may result in symptomatic hypotension. Alcohol can also enhance Fildena’s hypotensive effects, warranting moderation. Physicians should review all concurrent medications and advise accordingly.

Side Effects

Common side effects of sildenafil 100 mg include headache, flushing, and dyspepsia. These are generally mild and transient. Nasal congestion and dizziness may also occur.

Rarely, patients may experience vision changes, such as altered color perception. More severe adverse reactions necessitate immediate medical attention. These include chest pain, severe hypotension, or prolonged erections lasting over four hours.

Fildena Over The Counter

Fildena is not available over the counter. It requires a prescription due to potential contraindications and interactions. This ensures patient safety and appropriate use.

Healthcare professionals evaluate individual health profiles before recommending Fildena. This evaluation considers cardiovascular status and other medications. Patients should consult their healthcare provider to determine if Fildena is suitable for them.

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